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Rapid method for the determination of 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in small regions of rat brain
British Journal of Pharmacology · 1970 · Vol. 39(3) · pp. 653–655
G. Curzon✉(National Hospital for Neurology and Neurosurgery)A. R. Green(National Hospital for Neurology and Neurosurgery)
Abstract
A rapid and sensitive method for measuring 5-hydroxytryptamine and 5-hydroxyindoleacetic acid, using o-phthalaldehyde and L-cysteine, is presented, enabling both compounds to be measured in small areas of rat brain.
Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and MetabolismMetabolomics and Mass Spectrometry Studies5-Hydroxyindoleacetic acidNeuroscienceSerotoninPsychologyMedicineInternal medicine
MeSH terms
AldehydesAnimalsBrain ChemistryCysteineFluorometryHydroxyindoleacetic AcidMaleMethodsSerotoninRats
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935
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References
REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I
Journal of Neurochemistry · 1966 · 5,438 citations
A sensitive and specific fluorescence assay for tissue serotonin
Biochemical Pharmacology · 1965 · 530 citations
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