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5-(3-carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans As cell-viability indicators

Bioorganic & Medicinal Chemistry Letters · 1991 · Vol. 1(11) · pp. 611–614
J. A. Barltrop✉Terence C. OwenAnn H. CoryJoseph G. Cory
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bioluminescence and chemiluminescence researchAnimal testing and alternativesAntimicrobial agents and applicationsChemistryBromideSalt (chemistry)FormazanSalt waterStereochemistryBiochemistryOrganic chemistry
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447
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0.71
field-weighted impact
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9
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67%
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Citations per year
References
Rapid colormetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines
Journal of Immunological Methods · 1984 · 561 citations
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
Journal of Immunological Methods · 1983 · 55,054 citations
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5-(3-carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans As cell-viability indicators · Scinovex