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Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation

British Journal of Ophthalmology · 2005 · Vol. 90(1) · pp. 75–80

Jane C. Khan✉(University of Cambridge)

Abstract

The authors have demonstrated a strong association between the risk of both GA and CNV and pack years of cigarette smoking. This provides support for a causal relation between smoking and AMD. They also show an increased risk for AMD in non-smokers exposed to passive smoking. Stopping smoking appears to reduce the risk of developing AMD.

Retinal Diseases and Treatments Retinal Imaging and Analysis Glaucoma and retinal disordersMedicineMacular degenerationGeographic atrophyOphthalmologyAtrophyCigarette smokingChoroidDegeneration (medical)OptometryRetina

MeSH terms

AgedAged, 80 and overAtrophyFemaleHumansMacular DegenerationMalePigment Epithelium of EyeRisk FactorsSmokingTime FactorsTobacco Smoke PollutionCase-Control StudiesSmoking CessationChoroidal Neovascularization