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Role of reactive oxygen species in cell signalling pathways
Biochemical Society Transactions · 2001 · Vol. 29(2) · pp. 345–345
Abstract
Reactive oxygen species (ROS) were originally thought to only be released by phagocytic cells during their role in host defence. It is now clear that ROS have a cell signalling role in many biological systems, both in animals and in plants. ROS induce programmed cell death or necrosis, induce or suppress the expression of many genes, and activate cell signalling cascades, such as those involving mitogen-activated protein kinases.
Neutrophil, Myeloperoxidase and Oxidative MechanismsReactive oxygen speciesCell biologyProgrammed cell deathSignalling pathwaysSignal transductionKinaseSignallingCellBiologyMitogen-activated protein kinase
MeSH terms
AnimalsEnzyme ActivationGene Expression RegulationHumansIsoenzymesOxidation-ReductionPhosphorylationSignal TransductionReactive Oxygen SpeciesOxidative StressNADPH Oxidases
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