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Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients

The American Journal of Gastroenterology · 2014 · Vol. 109(7) · pp. 1065–1071

Colleen Kelly✉(Brown University)Chioma Ihunnah(Brown University)Monika Fischer(Indiana University School of Medicine)Alexander Khoruts(University of Minnesota Medical Center)Christina M. Surawicz(University of Washington)Anita Afzali(University of Washington)Olga C. Aroniadis(Montefiore Medical Center)Amy Barto(Tufts University)Thomas J. Borody(Centre For Digestive Diseases)Andrea Giovanelli(Northern California Research)Shelley Gordon(California Pacific Medical Center)Michael Glück(Virginia Mason Medical Center)Elizabeth Hohmann(Massachusetts General Hospital)Dina Kao(University of Alberta)John Y. Kao(University of Michigan–Ann Arbor)Daniel P. McQuillen(Tufts University)Mark Mellow(INTEGRIS Baptist Medical Center)Kevin Rank(University of Minnesota Medical Center)Krishna Rao(University of Michigan–Ann Arbor)Arnab Ray(Ochsner Medical Center)Margot A. Schwartz(Virginia Mason Medical Center)Namita Singh(Seattle Children's Hospital)Neil Stollman(Northern California Research)David L. Suskind(Seattle Children's Hospital)Stephen M. Vindigni(University of Washington)Ilan Youngster(Massachusetts General Hospital)Lawrence J. Brandt(Albert Einstein College of Medicine)

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Abstract

This series demonstrates the effective use of FMT for CDI in IC patients with few SAEs or related AEs. Importantly, there were no related infectious complications in these high-risk patients.

Clostridium difficile and Clostridium perfringens research Microscopic Colitis Gut microbiota and healthMedicineClostridium difficileAdverse effectRefractory (planetary science)Internal medicineRetrospective cohort studyTransplantationMedical recordSurgeryGastroenterology

MeSH terms

AdolescentAdultAgedAged, 80 and overChildEnterocolitis, PseudomembranousFecesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesRetrospective StudiesClostridioides difficileImmunocompromised Host

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635

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41.89

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Cited by

Systematic review with meta‐analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection