articleTop 1% cited
Calcineurin Inhibitor Nephrotoxicity: Longitudinal Assessment by Protocol Histology
Transplantation · 2004 · Vol. 78(4) · pp. 557–565
Brian J. Nankivell✉(Westmead Hospital)Richard Borrows(Westmead Hospital)Caroline FungPhilip J. O’Connell(The University of Sydney)Jeremy R. Chapman(Westmead Hospital)Richard D. Allen
Abstract
Pathologic changes of CsA nephrotoxicity were virtually universal by 10 years and exacerbated chronic allograft nephropathy. CsA is unsuitable as a universal, long-term immunosuppressive agent for kidney transplantation. Strategies to ameliorate or avoid nephrotoxicity are thus urgently needed.
Renal Transplantation Outcomes and TreatmentsOrgan Donation and TransplantationTransplantation: Methods and OutcomesNephrotoxicityMedicineUrologyNephropathyChronic allograft nephropathyGlomerulosclerosisFibrosisTransplantationKidneyKidney transplantation
MeSH terms
AdultArteriolesFemaleHumansImmunosuppressive AgentsKidneyLongitudinal StudiesMaleMiddle AgedProspective StudiesKidney TransplantationCyclosporineCalcineurin Inhibitors
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References
The Banff 97 working classification of renal allograft pathology
Kidney International · 1999 · 3,045 citations
International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology
Kidney International · 1993 · 1,458 citations
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