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Analysis of Gene Diversity in Subdivided Populations

Proceedings of the National Academy of Sciences · 1973 · Vol. 70(12) · pp. 3321–3323
Masatoshi Nei

Abstract

A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This method is applicable to any population without regard to the number of alleles per locus, the pattern of evolutionary forces such as mutation, selection, and migration, and the reproductive method of the organism used. Measures of the absolute and relative magnitudes of gene differentiation among subpopulations are also proposed.

Genetic diversity and population structureGenetic Mapping and Diversity in Plants and AnimalsChromosomal and Genetic VariationsLoss of heterozygosityBiologyLocus (genetics)GeneticsAlleleGeneEvolutionary biologyPopulationGene poolGenetic diversity

MeSH terms

AllelesGene FrequencyGenetics, PopulationHeterozygoteModels, BiologicalGenetic Variation

Funding

  • U.S. Public Health Service
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