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Acetylenes in Catalysis: Enantioselective Additions to Carbonyl Groups and Imines and Applications Beyond

European Journal of Organic Chemistry · 2004 · Vol. 2004(20) · pp. 4095–4105

Pier Giorgio Cozzi✉Robert Hilgraf✉(Bristol-Myers Squibb (Switzerland))Nici Zimmermann✉(Vertex Pharmaceuticals (United States))

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Abstract

Abstract Acetylenes represent a class of versatile building blocks, which are widely used in organic synthesis. Over the past years, a considerable number of publications have appeared that focus on the enantioselective addition of acetylenes to carbonyls and imines. In addition, novel applications for acetylenes have emerged in the literature. We herein present an overview of recent results in these areas. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

Chemical Synthesis and Analysis Fluorine in Organic Chemistry Click Chemistry and ApplicationsEnantioselective synthesisChemistryOrganic chemistryCatalysisCombinatorial chemistryOrganic synthesis

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