review Open AccessTop 1% cited
Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells
Cell stem cell · 2011 · Vol. 8(5) · pp. 486–498
Érika Pastrana✉(Columbia University Irving Medical Center)Violeta Silva-Vargas(Columbia University Irving Medical Center)Fiona Doetsch(Columbia University Irving Medical Center)
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanismsPlanarian Biology and ElectrostimulationNeurosphereStem cellBiologyContext (archaeology)Computational biologyCell biologyStem cell nicheNicheIn vivoIn vitro
MeSH terms
AnimalsCell DifferentiationCell SurvivalColony-Forming Units AssayHumansResearch DesignStem CellsCell Culture Techniques
Funding
- David and Lucile Packard Foundation
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke
Citations
828
FWCI
29.14
field-weighted impact
References
103
Percentile
100%
vs. same field & year
Citations per year
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References
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European Journal of Neuroscience · 1999 · 544 citations
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Journal of Neuroscience · 1997 · 1,891 citations
Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell
PLoS Biology · 2005 · 873 citations
Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain
Cell stem cell · 2008 · 1,001 citations
Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions
Cell stem cell · 2008 · 1,017 citations
Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens
Cell stem cell · 2009 · 1,043 citations
A Specialized Vascular Niche for Adult Neural Stem Cells
Cell stem cell · 2008 · 1,009 citations
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
Genes & Development · 2003 · 2,396 citations
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