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A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation
American Heart Journal · 2006 · Vol. 153(1) · pp. 66.e9–66.e16
John T. Brandt✉(Eli Lilly (United States))Christopher D. Payne(Eli Lilly (United States))Stephen D. Wiviott(Thrombolysis in Myocardial Infarction Study Group)Govinda Weerakkody(Eli Lilly (United States))Nagy A. Farid(Eli Lilly (United States))David S. Small(Eli Lilly (United States))Joseph A. Jakubowski(Eli Lilly (United States))Hideo Naganuma(Daiichi-Sankyo (Japan))Kenneth J. Winters(Eli Lilly (United States))
Antiplatelet Therapy and Cardiovascular DiseasesLipoproteins and Cardiovascular HealthPharmacology and Obesity TreatmentPrasugrelMedicineClopidogrelActive metabolitePlateletPlatelet inhibitionMetabolitePharmacologyLoading doseInternal medicine
MeSH terms
Prasugrel HydrochlorideClopidogrelAdultBlood PlateletsFemaleHumansMaleMiddle AgedPiperazinesPlatelet Aggregation InhibitorsThiophenesTiclopidineCross-Over StudiesArea Under CurvePurinergic P2 Receptor Antagonists
Citations
568
FWCI
30.37
field-weighted impact
References
38
Percentile
100%
vs. same field & year
Citations per year
Cited by
Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes
New England Journal of Medicine · 2007 · 6,705 citations
References
Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
Thrombosis and Haemostasis · 2003 · 584 citations
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