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Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naïve patients

AIDS · 2000 · Vol. 14(5) · pp. 499–507
Antonella d’Arminio MonforteAlessandro Cozzi‐LepriGiovanni RezzaPatrizio PezzottiAndrea AntinoriAndrew N. PhillipsGioacchino AngaranoVincenzo ColangeliAndrea De LucaGiuseppe IppolitoL CaggeseFabrizio SosciaG. FiliceFabrice GrittiPasquale NarcisoUmberto TirelliMauro Moroni

Abstract

If the current HAART regimen caused no toxicity, less than 10% of naïve patients discontinue their first HAART regimen because of failure after 1 year from starting therapy.

HIV/AIDS drug development and treatmentHIV Research and TreatmentHIV/AIDS Research and InterventionsDiscontinuationMedicineRegimenInternal medicineRitonavirIndinavirPopulationHazard ratioConfidence intervalReverse-transcriptase inhibitor

MeSH terms

AdultAgedDrug Therapy, CombinationHIV SeropositivityHumansItalyMaleMiddle AgedTime FactorsCohort StudiesHIV InfectionsTreatment RefusalTreatment FailureHIV Protease InhibitorsReverse Transcriptase Inhibitors
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