article Open AccessTop 1% cited
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
Nature Neuroscience · 2012 · Vol. 15(5) · pp. 793–802
Linda Madisen✉(Allen Institute)Tianyi Mao(Oregon Health & Science University)Henner Koch(Seattle Children's Hospital)Jia-Min Zhuo(Boston University)Antal Berényi(Rutgers, The State University of New Jersey)Shigeyoshi Fujisawa(Rutgers, The State University of New Jersey)Yun‐Wei A. Hsu(Seattle Children's Hospital)Alfredo J. Garcia(Seattle Children's Hospital)Xuan Gu(Boston University)Sébastien Zanella(Seattle Children's Hospital)Jolene Kidney(Allen Institute)Hong Gu(Allen Institute)Yimei Mao(Boston University)Bryan M. Hooks(Janelia Research Campus)Edward S. Boyden(Massachusetts Institute of Technology)György Buzsáki(Rutgers, The State University of New Jersey)Jan‐Marino Ramirez(Seattle Children's Hospital)Allan R. Jones(Allen Institute)Karel Svoboda(Howard Hughes Medical Institute)Xue Han(Boston University)Eric E. Turner(Seattle Children's Hospital)Hongkui Zeng(Allen Institute for Brain Science)
Photoreceptor and optogenetics researchNeuroscience and Neural EngineeringNeural dynamics and brain functionOptogeneticsTransgeneChannelrhodopsinNeuroscienceHalorhodopsinGene silencingBiologyCell biologyParvalbuminGreen fluorescent protein
MeSH terms
ChannelrhodopsinsAction PotentialsAnimalsBrainLightLuminescent ProteinsMice, TransgenicNeuronsProteinsWakefulnessProton PumpsElectroporationIntegrasesArchaeal ProteinsRNA, Untranslated
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References
A high-light sensitivity optical neural silencer: development, and application to optogenetic control of nonhuman primate cortex
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Neuron · 2011 · 2,007 citations
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
Nature Neuroscience · 2009 · 7,243 citations
Accuracy of Tetrode Spike Separation as Determined by Simultaneous Intracellular and Extracellular Measurements
Journal of Neurophysiology · 2000 · 1,202 citations
Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses
Current Biology · 2005 · 1,014 citations
Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat
The Journal of Comparative Neurology · 1990 · 895 citations
Millisecond-timescale, genetically targeted optical control of neural activity
Nature Neuroscience · 2005 · 4,871 citations
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