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BONE FORMATION IN VIVO: COMPARISON OF OSTEOGENESIS BY TRANSPLANTED MOUSE AND HUMAN MARROW STROMAL FIBROBLASTS

Transplantation · 1997 · Vol. 63(8) · pp. 1059–1069

Paul H. Krebsbach(National Institutes of Health)Sergei A. Kuznetsov(National Institute of Dental and Craniofacial Research)Kazuhito Satomura(National Institutes of Health)Robert Emmons(National Heart Lung and Blood Institute)David W. RowePamela Gehron Robey✉(National Institutes of Health)

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Abstract

In this article, we describe the differences in the requirements for mouse and human MSFs to form bone, and report the development of a methodology for the consistent in vivo generation of extensive bone from human MSFs.

Mesenchymal stem cell research Periodontal Regeneration and Treatments Bone Tissue Engineering MaterialsTransplantationAscorbic acidProcollagen peptidaseChemistryStromal cellMolecular biologyInternal medicineBiologyMedicine

MeSH terms

AnimalsBone DevelopmentBone Marrow CellsCalcium PhosphatesCells, CulturedCeramicsChildChild, PreschoolCollagenFemaleFibroblastsHumansMaleMice, TransgenicOsteogenesis

Citations

483

FWCI

10.73

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99%

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Cited by

Single-Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo