reviewTop 10% cited
Tear Film Osmolarity: Determination of a Referent for Dry Eye Diagnosis
Investigative Ophthalmology & Visual Science · 2006 · Vol. 47(10) · pp. 4309–4309
Alan Tomlinson✉Santosh KhanalKanna Ramaesh(Gartnavel General Hospital)Charles DiaperAngus McFadyen(Glasgow Caledonian University)
Abstract
Tear hyperosmolarity, defined by a referent of 316 mOsmol/L, was superior in overall accuracy to any other single test for dry eye diagnosis (Lactoplate, Schirmer test, and Rose Bengal staining), even when the other test measures were applied to a diagnosis within the sample groups from which they were derived. For overall accuracy in the diagnosis of dry eye, the osmolarity test was found to be comparable with the results of combined (in parallel or series) tests.
Ocular Surface and Contact LensGlaucoma and retinal disordersContact Dermatitis and AllergiesReceiver operating characteristicOsmotic concentrationOphthalmologyMedicineCutoffInternal medicine
MeSH terms
False Positive ReactionsHumansKeratoconjunctivitis SiccaOsmolar ConcentrationPredictive Value of TestsROC CurveSensitivity and SpecificityTears
Citations
563
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Archives of Ophthalmology · 1969 · 1,082 citations
Prevalence of and Risk Factors for Dry Eye Syndrome
Archives of Ophthalmology · 2000 · 1,209 citations
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