reviewTop 10% cited
Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
Vaccine · 2000 · Vol. 18(16) · pp. 1717–1720
Claudio Franceschi✉(University of Bologna)Massimiliano Bonafè(University of Bologna)Silvana Valensin(University of Bologna)
T-cell and B-cell ImmunologySingle-cell and spatial transcriptomicsCytomegalovirus and herpesvirus researchImmunosenescenceBiologyImmunologyImmunityAntigenInnate immune systemImmune system
MeSH terms
AgedAged, 80 and overAgingAntigensCell DivisionBiological EvolutionHumansImmunity, InnateImmunologic MemoryLymphocyte ActivationModels, BiologicalStress, PhysiologicalT-LymphocytesTelomere
Citations
489
FWCI
4.27
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95%
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References
Increased cytokine production in mononuclear cells of healthy elderly people
European Journal of Immunology · 1993 · 649 citations
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