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Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men

AIDS · 2003 · Vol. 17(17) · pp. 2479–2486
Murielle Mary‐KrauseLaurent CotteAnne SimonM PartisaniDominique Costagliola

Abstract

Our results point to a duration-related effect relationship between PI and MI, with a higher MI incidence rate among men exposed to PI for 18 months or more.

HIV-related health complications and treatmentsHIV/AIDS drug development and treatmentHIV Research and TreatmentMedicineHazard ratioConfidence intervalContext (archaeology)Internal medicineMyocardial infarctionRelative riskPopulationProportional hazards modelIncidence (geometry)

MeSH terms

AdultFranceHumansMaleMyocardial InfarctionProtease InhibitorsRisk FactorsTime FactorsHIV InfectionsIncidenceProportional Hazards ModelsReverse Transcriptase InhibitorsAnti-Retroviral Agents

Funding

  • Styrelsen för Internationellt Utvecklingssamarbete
  • Institut National de la Santé et de la Recherche Médicale
  • Fondation pour la Recherche Médicale
Citations
564
FWCI
42.25
field-weighted impact
References
32
Percentile
100%
vs. same field & year
Citations per year
References
Hypertriglyceridemia as a Cardiovascular Risk Factor
The American Journal of Cardiology · 1998 · 1,070 citations
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Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men · Scinovex