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Characterization of Behavioral and Neurodegenerative Changes Following Partial Lesions of the Nigrostriatal Dopamine System Induced by Intrastriatal 6-Hydroxydopamine in the Rat

Experimental Neurology · 1998 · Vol. 152(2) · pp. 259–277
Deniz KirikCarl RosenbladAnders Björklund
Parkinson's Disease Mechanisms and TreatmentsNeurotransmitter Receptor Influence on BehaviorBotulinum Toxin and Related Neurological DisordersStriatumGlobus pallidusForelimbHydroxydopamineLesionSubstantia nigraDopamineTyrosine hydroxylaseBasal gangliaNeuroscience

MeSH terms

AmphetamineAnimalsApomorphineCorpus StriatumDopamineFemaleForelimbMicroinjectionsMotor ActivityNerve DegenerationNeuronsPsychomotor PerformanceRotationSubstantia NigraTyrosine 3-Monooxygenase

Funding

  • European Commission
  • Knut och Alice Wallenbergs Stiftelse
  • Medical Research Council
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