articleTop 1% cited
Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency
Journal of Controlled Release · 2001 · Vol. 70(3) · pp. 399–421
Hai‐Quan Mao(Johns Hopkins Medicine)Krishnendu Roy(Johns Hopkins University)Vu L. Troung-Le(Johns Hopkins University)Kevin A. Janes(Johns Hopkins University)Kevin Lin(Johns Hopkins University)Yan Wang(Johns Hopkins Medicine)J. Thomas August(Johns Hopkins Medicine)Kam W. Leong✉(Johns Hopkins University)
RNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryChitosanCoacervateChemistryNanoparticleTransfectionZeta potentialLipofectamineGene deliveryNuclear chemistryDNA
MeSH terms
AnimalsCell LineChitinChloroquineDNAHumansMice, Inbred AKRPolyethylene GlycolsTissue DistributionTransfectionGenetic TherapyChitosanMice
Citations
1,219
FWCI
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References
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99%
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References
Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability
Pharmaceutical Research · 1998 · 533 citations
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.
Proceedings of the National Academy of Sciences · 1995 · 6,198 citations
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry · 1983 · 25,153 citations
Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA
International Journal of Pharmaceutics · 1999 · 525 citations
In vitro evaluation of the mucoadhesive properties of chitosan microspheres
International Journal of Pharmaceutics · 1998 · 656 citations
Molecular cloning: A laboratory manual
Analytical Biochemistry · 1990 · 86,156 citations
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