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Retinal thickness decreases with age: an OCT study
British Journal of Ophthalmology · 2003 · Vol. 87(7) · pp. 899–901
B Alamouti✉(University Medical Center Freiburg)
Abstract
Using OCT scans the total retinal thickness can be calculated with high reproducibility (coefficient of variation = 3.5%). The reproducibility of nerve fibre layer thickness measurements is clearly lower (coefficient of variation = 8.0%). Both the total retinal thickness and the nerve fibre layer thickness significantly decrease with age. This influence of the age related decrease in RNFL/retinal thickness on the reference plane, however, is negligible.
Glaucoma and retinal disordersRetinal Imaging and AnalysisOptical Coherence Tomography ApplicationsMedicineRetinalOphthalmologyOptometryRetinaOptics
MeSH terms
AdolescentAdultAgedAgingChildFemaleHumansLasersMaleMiddle AgedNerve FibersOptic DiskRetinaReproducibility of ResultsMicroscopy, Confocal
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References
The Effect of Age on the Nerve Fiber Population of the Human Optic Nerve
American Journal of Ophthalmology · 1984 · 496 citations
Quantification of Nerve Fiber Layer Thickness in Normal and Glaucomatous Eyes Using Optical Coherence Tomography
Archives of Ophthalmology · 1995 · 872 citations
Optical Coherence Tomography of the Human Retina
Archives of Ophthalmology · 1995 · 1,626 citations
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