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Synthesis of Functionalized Oxazolines and Oxazoles with DAST and Deoxo-Fluor
Organic Letters · 2000 · Vol. 2(8) · pp. 1165–1168
Andrew J. Phillips✉(University of Pittsburgh)Yoshikazu Uto(Indiana University Bloomington)Peter Wipf(Indiana University Bloomington)Michael J. Reno(University of Pittsburgh)David R. Williams(University of Pittsburgh)
Abstract
[formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.
Synthetic Organic Chemistry MethodsSynthesis and Catalytic ReactionsChemical Synthesis and AnalysisChemistryReagentCombinatorial chemistryOrganic chemistry
MeSH terms
DiethylaminesFluorineIndicators and ReagentsOxazoles
Citations
460
FWCI
12.16
field-weighted impact
References
25
Percentile
99%
vs. same field & year
Citations per year
References
The chemistry of 2-oxazolines (1985–present)
Tetrahedron · 1994 · 564 citations
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