article Open AccessTop 10% cited
Ionic Liquids Then and Now: From Solvents to Materials to Active Pharmaceutical Ingredients
Bulletin of the Chemical Society of Japan · 2007 · Vol. 80(12) · pp. 2262–2269
Whitney L. Hough✉(University of Alabama)Robin D. Rogers(University of Alabama)
Abstract
Abstract Ionic liquids (ILs) have evolved from salts studied primarily for their physical properties (low melting salts which could be used as solvents) to tunable materials based upon the physical, chemical, and now even biological properties that can be introduced through either ion. In this perspective, we follow this interesting evolution with respect to our work in this growing field, and discuss possible future directions, such as the use of ILs as active pharmaceutical ingredients (APIs).
Ionic liquids properties and applicationsChemistry and Chemical EngineeringChemical and Physical Properties in Aqueous SolutionsChemistryActive ingredientIonic liquidOrganic chemistryChemical engineeringCatalysis
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References
The third evolution of ionic liquids: active pharmaceutical ingredients
New Journal of Chemistry · 2007 · 849 citations
Dialkylimidazolium chloroaluminate melts: a new class of room-temperature ionic liquids for electrochemistry, spectroscopy and synthesis
Inorganic Chemistry · 1982 · 1,425 citations
Characterization of Habits and Crystalline Modification of Solids and Their Pharmaceutical Applications
Journal of Pharmaceutical Sciences · 1975 · 480 citations
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