articleTop 10% cited

Randomized double-blind study of cyclosporin in chronic ‘idiopathic’ urticaria

British Journal of Dermatology · 2000 · Vol. 143(2) · pp. 365–372

Clive Grattan✉(Norfolk and Norwich University Hospital)B. F. O’Donnell(Institute of Dermatology)David M. Francis(St. John's University)N. Niimi(Institute of Dermatology)Richard Barlow(St. John's University)Paul T. SeedA. Kobza Black(St. John's University)Malcolm W. Greaves(St. John's University)

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Abstract

This study shows that cyclosporin is effective for chronic urticaria and provides further evidence for a role of histamine-releasing autoantibodies in the pathogenesis of this chronic 'idiopathic' disease.

Urticaria and Related Conditions Autoimmune Bullous Skin Diseases Dermatology and Skin DiseasesMedicineRandomized controlled trialDermatologyDouble blindChronic idiopathic urticariaChronic urticariaInternal medicinePathologyPlaceboAlternative medicine

MeSH terms

AdultAgedAlgorithmsBasophilsChronic DiseaseDermatologic AgentsDouble-Blind MethodFemaleFollow-Up StudiesHistamine ReleaseHumansImmunosuppressive AgentsMaleMiddle AgedUrticaria

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407

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8.92

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The <scp>EAACI</scp>/<scp>GA</scp><sup>2</sup><scp>LEN</scp>/<scp>EDF</scp>/<scp>WAO</scp> Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update