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The JAK-STAT Pathway at Twenty

Immunity · 2012 · Vol. 36(4) · pp. 503–514
George R. StarkJames Darnell
Cytokine Signaling Pathways and Interactionsinterferon and immune responsesProtein Tyrosine PhosphatasesSTAT2BiologyJAK-STAT signaling pathwaySUMO proteinSTAT1Cell biologyPhosphorylationSTAT proteinJanus kinase 1STAT6

MeSH terms

AnimalsChromatinHumansInterferon Type IMitochondriaProtein Processing, Post-TranslationalTranscription, GeneticSignal TransductionSTAT Transcription FactorsInterferon Regulatory FactorsJanus Kinases
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References
STATs: transcriptional control and biological impact
Nature Reviews Molecular Cell Biology · 2002 · 3,165 citations
G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS
Annual Review of Biochemistry · 1987 · 6,407 citations
HOW CELLS RESPOND TO INTERFERONS
Annual Review of Biochemistry · 1998 · 3,942 citations
INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS
Annual Review of Biochemistry · 1987 · 3,299 citations
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The JAK-STAT Pathway at Twenty · Scinovex