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Simplified criteria for the diagnosis of autoimmune hepatitis†

Hepatology · 2008 · Vol. 48(1) · pp. 169–176

Elke Hennes(University Medical Center Hamburg-Eppendorf)Mikio Zeniya(Jikei University School of Medicine)Albert J. Czaja(Mayo Clinic in Arizona)Albert ParésGeorge N. Dalekos(University of Thessaly)Edward L. Krawitt(University of Vermont)Paulo Lisboa Bittencourt(Universidade de São Paulo)Gilda Porta(Universidade de São Paulo)Kirsten Muri BobergHarald Hofer(Medical University of Vienna)Francesco B. Bianchi(University of Bologna)Minoru Shibata(NTT Medical Center)Christoph Schramm(University Medical Center Hamburg-Eppendorf)Bárbara Torres(Johannes Gutenberg University Mainz)Peter R. Galle(Johannes Gutenberg University Mainz)Ian G. McFarlane(King's College Hospital)Hans‐Peter DienesAnsgar W. Lohse✉(GTx (United States))

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Abstract

A reliable diagnosis of AIH can be made using a very simple diagnostic score. We propose the diagnosis of probable AIH at a cutoff point greater than 6 points and definite AIH 7 points or higher.

Liver Diseases and Immunity Liver Disease Diagnosis and Treatment Systemic Lupus Erythematosus ResearchReceiver operating characteristicAutoimmune hepatitisMedicineCutoffInternal medicineAutoantibodyHepatitisGastroenterologyImmunologyAntibody

MeSH terms

AdultDiagnostic Techniques, Digestive SystemGastroenterologyHumansInternational CooperationMiddle AgedRetrospective StudiesROC CurveSensitivity and SpecificityReproducibility of ResultsCohort StudiesPractice Guidelines as TopicArea Under CurveHepatitis, Autoimmune