reviewTop 1% cited
Toll-like receptors: From the discovery of NFκB to new insights into transcriptional regulations in innate immunity
Biochemical Pharmacology · 2006 · Vol. 72(9) · pp. 1102–1113
Sarah Doyle✉(Trinity College Dublin)Luke O'neill(Trinity College Dublin)
Immune Response and InflammationNF-κB Signaling PathwaysNeutrophil, Myeloperoxidase and Oxidative MechanismsInnate immune systemBiologyPattern recognition receptorReceptorTLR4Signal transductionCell biologyToll-like receptorImmune systemImmunology
MeSH terms
AnimalsHumansImmunity, InnateProtein-Tyrosine KinasesTranscription, GeneticSignal TransductionTranscriptional ActivationNF-kappa BToll-Like Receptors
Funding
- Science Foundation Ireland
Citations
590
FWCI
13.56
field-weighted impact
References
106
Percentile
99%
vs. same field & year
Citations per year
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References
Unresponsiveness of MyD88-Deficient Mice to Endotoxin
Immunity · 1999 · 2,066 citations
MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways
Molecular Cell · 1998 · 1,557 citations
Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes
The Journal of Immunology · 2001 · 1,088 citations
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.
Molecular and Cellular Biology · 1990 · 1,384 citations
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
Annual Review of Immunology · 2000 · 4,725 citations
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
The Journal of Immunology · 2002 · 1,222 citations
Function and Activation of NF-kappaB in the Immune System
Annual Review of Immunology · 1994 · 4,706 citations
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