articleTop 10% cited
Dementia and Alzheimer Disease Incidence
Archives of Neurology · 2002 · Vol. 59(11) · pp. 1737–1737
Walter A. Kukull✉(University of Washington)Roger Higdon(University of Washington)James D. Bowen(University of Washington)Wayne C. McCormick(University of Washington)Linda Teri(University of Washington)Gerard D. SchellenbergGerald van Belle(University of Washington)Lance Jolley(University of Washington)Eric B. Larson(University of Washington)
Abstract
Our dementia and AD incidence rates are consistent with recent US and European cohort studies, providing clinicians and researchers new information concerning the reproducibility of incidence estimates across settings. Increased risk was associated with age and the apolipoprotein E genotype; also with a low baseline cognitive screening test score. Educational level was inversely associated with the risk of dementia and positively associated with the baseline cognitive test score; thus, detection of AD by the screening test could also be influenced by educational level.
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsHealth Systems, Economic Evaluations, Quality of LifeDementiaIncidence (geometry)MedicinePopulationGerontologyPoisson regressionDemographyCohortCohort studyConfidence interval
MeSH terms
Age FactorsAgedAged, 80 and overAlzheimer DiseaseApolipoproteins EDementiaFemaleFollow-Up StudiesHumansMaleProspective StudiesRisk FactorsCohort StudiesIncidenceConfidence Intervals
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References
Clinical diagnosis of Alzheimer's disease
Neurology · 1984 · 27,910 citations
The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects
The British Journal of Psychiatry · 1968 · 4,104 citations
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