review Open AccessTop 1% cited
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
Cell Metabolism · 2009 · Vol. 9(5) · pp. 407–416
Bei B. Zhang✉(Merck & Co., Inc., Rahway, NJ, USA (United States))Gaochao Zhou(Merck & Co., Inc., Rahway, NJ, USA (United States))Li Cai(Merck & Co., Inc., Rahway, NJ, USA (United States))
Metabolism, Diabetes, and CancerPancreatic function and diabetesDiet, Metabolism, and DiseaseAMPKDiabetes mellitusMetabolic syndromeDrugMedicineMetforminDrug discoveryInternal medicinePharmacologyBioinformatics
MeSH terms
Diabetes Mellitus, Type 2HumansHypoglycemic AgentsInsulinLiverMusclesMetabolic SyndromeAMP-Activated Protein Kinases
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References
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Cell Metabolism · 2008 · 1,952 citations
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
Nature Medicine · 2002 · 4,196 citations
AMPK: a key regulator of energy balance in the single cell and the whole organism
International Journal of Obesity · 2008 · 681 citations
Role of AMP-activated protein kinase in mechanism of metformin action
Journal of Clinical Investigation · 2001 · 5,364 citations
Mechanism by which metformin reduces glucose production in type 2 diabetes.
Diabetes · 2000 · 1,045 citations
Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy
Diabetes Care · 2008 · 3,831 citations
Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes
Diabetes · 2002 · 2,298 citations
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
American Journal of Physiology-Endocrinology and Metabolism · 1999 · 1,087 citations
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