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Pancreaticoduodenectomy for Cancer of the Head of the Pancreas 201 Patients

Annals of Surgery · 1995 · Vol. 221(6) · pp. 721–733

Charles J. Yeo✉(Johns Hopkins University)John L. Cameron✉(Johns Hopkins University)Keith D. Lillemoe✉(Johns Hopkins University)James V. Sitzmann✉(Johns Hopkins University)Ralph H. Hruban(Johns Hopkins University)Steven N. Goodman(Johns Hopkins University)William C. Dooley✉(Johns Hopkins University)JoAnn Coleman✉(Johns Hopkins University)Henry A. Pitt✉(Johns Hopkins University)

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Abstract

The survival of patients with pancreatic adenocarcinoma treated by pancreaticoduodenectomy is improving. Aspects of tumor biology, such as DNA content, tumor diameter, nodal status and margin status, are the strongest predictors of outcome.

Pancreatic and Hepatic Oncology Research Cholangiocarcinoma and Gallbladder Cancer Studies Cancer Genomics and DiagnosticsMedicinePancreaticoduodenectomyAdenocarcinomaSurgerySurvival ratePancreasPancreatic cancerSurvival analysisCancerInternal medicine

MeSH terms

Actuarial AnalysisAdenocarcinomaAgedCombined Modality TherapyDNA, NeoplasmFemaleFollow-Up StudiesHumansMaleMiddle AgedPancreatic NeoplasmsSurvival RateMultivariate AnalysisPancreaticoduodenectomyTreatment Outcome

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948

FWCI

20.42

field-weighted impact

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100%

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Cited by

Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma