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Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis

British Journal of Cancer · 2014 · Vol. 112(3) · pp. 580–593

Vincenzo Bagnardi✉(University of Milano-Bicocca)Matteo Rota(University of Milano-Bicocca)Edoardo Botteri(Ripamonti)Irene Tramacere(Fondazione IRCCS Istituto Neurologico Carlo Besta)Farhad Islami(Icahn School of Medicine at Mount Sinai)Veronika Fedirko(Emory University)Lorenza Scotti(University of Milano-Bicocca)Mazda Jenab(Centre International de Recherche sur le Cancer)Federica Turati(Istituti di Ricovero e Cura a Carattere Scientifico)Elena Pasquali(Ripamonti)Claudio Pelucchi(Istituti di Ricovero e Cura a Carattere Scientifico)Carlotta Galeone(Istituti di Ricovero e Cura a Carattere Scientifico)Rino Bellocco(Karolinska Institutet)Eva Negri(Mario Negri Institute for Pharmacological Research)Giovanni Corrao(University of Milano-Bicocca)Paolo Boffetta(Icahn School of Medicine at Mount Sinai)Carlo La Vecchia(University of Milan)

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Abstract

Alcohol increases risk of cancer of oral cavity and pharynx, oesophagus, colorectum, liver, larynx and female breast. There is accumulating evidence that alcohol drinking is associated with some other cancers such as pancreas and prostate cancer and melanoma.

Alcohol Consumption and Health Effects Nutritional Studies and Diet Liver Disease Diagnosis and TreatmentMeta-analysisAlcohol consumptionMedicineOncologyInternal medicineBioinformaticsAlcoholBiology

MeSH terms

Esophageal Squamous Cell CarcinomaAlcohol DrinkingBreast NeoplasmsCarcinoma, Squamous CellDose-Response Relationship, DrugEsophageal NeoplasmsFemaleHumansMaleMelanomaMouth NeoplasmsNeoplasmsPharyngeal NeoplasmsProstatic NeoplasmsRisk Factors