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The Theory of Tracer Experiments with <sup>131</sup>I-Labelled Plasma Proteins

Physics in Medicine and Biology · 1957 · Vol. 2(1) · pp. 36–53
C. M. E. Matthews

Abstract

Using the tracer theory of Rescigno, adapted for an open mammillary system, a method is given of finding (1) metabolic rate, (2) ratios of masses of protein in extravascular compartments to mass of protein in intravascular compartment, (3) capillary permeabilities, when 131I-labelled protein is injected into the blood stream of animals. Examples are given for human, rabbit and rat.

Adipose Tissue and MetabolismMuscle metabolism and nutritionBiochemical effects in animalsTRACERCompartment (ship)Blood proteinsBlood streamRadioactive tracerChemistryBiophysicsRadiochemistryPhysicsBiology

MeSH terms

Blood ProteinsHumansIodineIodine RadioisotopesRadioisotopes
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References
DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION
Journal of Biological Chemistry · 1949 · 16,131 citations
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