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Depression as a Risk Factor for Coronary Artery Disease: Evidence, Mechanisms, and Treatment

Psychosomatic Medicine · 2004 · Vol. 66(3) · pp. 305–315
Heather S. Lett

Abstract

There is substantial evidence for a relationship between depression and adverse clinical outcomes. However, despite the availability of effective therapies for depression, there is a paucity of data to support the efficacy of these interventions to improve clinical outcomes for depressed CAD patients. Randomized clinical trials are needed to further evaluate the value of treating depression in CAD patients to improve survival and reduce morbidity.

Cardiac Health and Mental HealthHeart Rate Variability and Autonomic ControlCardiovascular Issues in PregnancyCoronary artery diseaseDepression (economics)MedicineRisk factorDiseaseInternal medicineRandomized controlled trialPsychological interventionClinical trialIntensive care medicine

MeSH terms

Alcohol DrinkingAntidepressive AgentsCause of DeathCoronary DiseaseDepressive DisorderDexamethasoneFemaleHumansHydrocortisoneLongitudinal StudiesMalePrognosisPsychotherapyPsychotherapy, GroupRisk Factors
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