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Highly Sensitive, Automated Immunoassay for Immunoglobulin Free Light Chains in Serum and Urine

Clinical Chemistry · 2001 · Vol. 47(4) · pp. 673–680

Abstract

We developed sensitive, automated immunoassays for kappa and lambda FLC measurements in serum and urine that should facilitate the assessment of patients with light chain abnormalities.

Monoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins ResearchComplement system in diseasesImmunoglobulin light chainImmunoassayAntibodyUrineKappaBence Jones proteinMolecular biologyChemistryMultiple myelomaMedicine

MeSH terms

AnimalsAntibody SpecificityAutoanalysisHumansImmunoassayImmunoglobulin kappa-ChainsImmunoglobulin lambda-ChainsLatexLupus Erythematosus, SystemicWaldenstrom MacroglobulinemiaMultiple MyelomaNephelometry and TurbidimetryReference StandardsSensitivity and SpecificitySheep
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Highly Sensitive, Automated Immunoassay for Immunoglobulin Free Light Chains in Serum and Urine · Scinovex