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Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.

Molecular Pharmacology · 1987 · Vol. 32(4) · pp. 497–504
Bernhard BrüneV. Ullrich
Heme Oxygenase-1 and Carbon MonoxideLipid metabolism and disordersNeonatal Health and BiochemistryGUCY1A3ChemistryGUCY1B3BiochemistryPhospholipase CPhospholipaseIntracellularSodium nitroprussideGTP'Cyclase

MeSH terms

Adenosine DiphosphateArachidonic AcidsCarbon MonoxideEnzyme ActivationEpinephrineCyclic GMPGuanylate CyclaseHumansNitroprussidePhospholipidsPlatelet AggregationProstaglandin Endoperoxides, SyntheticEpoprostenolThromboxane B2Arachidonic Acid
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The therapeutic potential of carbon monoxide
Nature Reviews Drug Discovery · 2010 · 1,596 citations
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Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. · Scinovex