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Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function.

Journal of Pharmacology and Experimental Therapeutics · 1996 · Vol. 279(3) · pp. 1453–1461
Cytokine Signaling Pathways and InteractionsSynthesis and biological activityInflammatory mediators and NSAID effectsCytokineArthritisPharmacologyMedicineBone resorptionImmune systemTumor necrosis factor alphaIn vivoOvalbuminEx vivo

MeSH terms

AnimalsArthritisBone ResorptionCollagenDisease Models, AnimalEnzyme InhibitorsFemaleImidazolesMaleMice, Inbred StrainsPyridinesRats, Inbred LewShock, SepticTumor Necrosis Factor-alphaArachidonic Acid
Citations
499
FWCI
12.21
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0
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Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. · Scinovex