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Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)
Journal of the American Academy of Dermatology · 2015 · Vol. 73(1) · pp. 37–49
Kim Papp✉(Probity Medical Research)Kristian Reich(Dermatologikum Hamburg)Craig L. Leonardi(Saint Louis University)Leon Kircik(Mount Sinai Medical Center)Sergio Chimenti(University of Rome Tor Vergata)Richard G. Langley(Dalhousie University)ChiaChi HuRandall M. StevensRobert M. DayKenneth B. Gordon(Northwestern University)Neil J. Korman(University Hospitals Cleveland Medical Center)C.E.M. Griffiths(University of Manchester)
Psoriasis: Treatment and PathogenesisPhosphodiesterase function and regulationAsthma and respiratory diseasesApremilastMedicinePsoriasisPlaque psoriasisRandomized controlled trialDermatologyPhosphodiesterase inhibitorPhosphodiesteraseInternal medicinePharmacology
MeSH terms
Administration, OralDouble-Blind MethodFemaleHumansMaleMiddle AgedPsoriasisSeverity of Illness IndexThalidomidePhosphodiesterase 4 Inhibitors
Funding
- Abbott Laboratories
- Amgen
- Eli Lilly and Company
- Pfizer
- Astellas Pharma US
- GlaxoSmithKline
- Merck
- Novartis
- 3M
- Biogen Idec
- Celgene
- AbbVie
- National Institute for Health and Care Research
- Galderma
- LEO Pharma
- Genentech
- Johnson and Johnson
- Allergan
- Merck Sharp and Dohme
- Sandoz
- Janssen Pharmaceuticals
Citations
659
FWCI
28.37
field-weighted impact
References
16
Percentile
100%
vs. same field & year
Citations per year
Cited by
Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate‐to‐severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2)
British Journal of Dermatology · 2015 · 472 citations
Psoriasis Pathogenesis and Treatment
International Journal of Molecular Sciences · 2019 · 1,924 citations
References
Guidelines of care for the management of psoriasis and psoriatic arthritis
Journal of the American Academy of Dermatology · 2008 · 765 citations
Guidelines of care for the management of psoriasis and psoriatic arthritis
Journal of the American Academy of Dermatology · 2008 · 1,202 citations
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