article Open AccessTop 1% cited
M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide
BMC Cancer · 2015 · Vol. 15(1) · pp. 577–577
Marie Genin✉(University of Namur)C. François(University of Namur)Antoine Fattaccioli(University of Namur)Martine Raes(University of Namur)Carine Michiels(University of Namur)
Abstract
These results evidence for the first time a clear protective effect of M2 on the contrary to M1 macrophages on etoposide-induced cancer cell apoptosis.
Immune cells in cancerPhagocytosis and Immune RegulationHistone Deacetylase Inhibitors ResearchCancer cellApoptosisTHP1 cell lineCancer researchAnnexinCell cultureMacrophage polarizationMolecular biologyEtoposideMacrophage
MeSH terms
Antineoplastic Agents, PhytogenicCell CommunicationCell DifferentiationEtoposideHumansMacrophage ActivationMacrophagesNeoplasmsCytokinesApoptosisInflammation MediatorsDrug Resistance, NeoplasmCell Line, Tumor
Funding
- Fonds De La Recherche Scientifique - FNRS
- Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture
- Université de Namur
Citations
1,094
FWCI
15.64
field-weighted impact
References
42
Percentile
99%
vs. same field & year
Citations per year
References
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