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Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathy

Clinical Endocrinology · 2000 · Vol. 52(3) · pp. 267–271

Martin N. Gerding✉(Academic Medical Center)Jolanda W. C. van der Meer(Academic Medical Center)M. Broenink(Academic Medical Center)Onno Bakker(Academic Medical Center)Wilmar M. Wiersinga(Academic Medical Center)Mark F. Prummel(Academic Medical Center)

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Abstract

TSH-R antibody levels correlate directly with clinical features of Graves' ophthalmopathy. The results support the hypothesis of a pathogenetic role of TSH-R antibodies and the TSH-R in the orbit of Graves' ophthalmopathy patients.

Ophthalmology and Eye Disorders Glaucoma and retinal disorders Pituitary Gland Disorders and TreatmentsMedicineInternal medicineEuthyroidAnti-thyroid autoantibodiesEndocrinologyThyrotropin receptorAutoantibodyGraves' diseaseGraves' ophthalmopathyAntibody

MeSH terms

AntibodiesAutoantibodiesFemaleGraves DiseaseHumansIodide PeroxidaseMaleMiddle AgedReceptors, ThyrotropinRegression AnalysisImmunoglobulins, Thyroid-Stimulating

Citations

321

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6.18

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97%

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Cited by

TSH-receptor autoimmunity in Graves' disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study

European Journal of Endocrinology · 2007 · 428 citations

References

Clinical activity score as a guide in the management of patients with Graves' ophthalmopathy

Clinical Endocrinology · 1997 · 984 citations

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