Scinovex
articleTop 1% cited

Nitric oxide as a secretory product of mammalian cells

The FASEB Journal · 1992 · Vol. 6(12) · pp. 3051–3064
Carl Nathan

Abstract

Evolution has resorted to nitric oxide (NO), a tiny, reactive radical gas, to mediate both servoregulatory and cytotoxic functions. This article reviews how different forms of nitric oxide synthase help confer specificity and diversity on the effects of this remarkable signaling molecule.

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension PharmacologyRenin-Angiotensin System StudiesNitric oxideChemistryCytotoxic T cellNitric oxide synthaseCell biologyMoleculeBiochemistryBiologyOrganic chemistryIn vitro

MeSH terms

Amino Acid OxidoreductasesAnimalsHumansNitric OxideTerminology as TopicNitric Oxide Synthase
Citations
4,383
FWCI
133.93
field-weighted impact
References
140
Percentile
100%
vs. same field & year
Citations per year
Cited by
CELLULAR RESPONSES TO INTERFERON-γ
Annual Review of Immunology · 1997 · 2,902 citations
Nitric oxide and the immune response
Nature Immunology · 2001 · 3,381 citations
The high-output nitric oxide pathway: role and regulation
Journal of Leukocyte Biology · 1994 · 510 citations
New insights into the regulation of inducible nitric oxide synthesis
American Journal of Physiology-Endocrinology and Metabolism · 1994 · 575 citations
Increased amount of nitric oxide in exhaled air of asthmatics
European Respiratory Journal · 1993 · 1,233 citations
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
Journal of Biological Chemistry · 1994 · 2,219 citations
Prolactin: Structure, Function, and Regulation of Secretion
Physiological Reviews · 2000 · 2,434 citations
Inflammation, immunoregulation, and inducible nitric oxide synthase
Journal of Leukocyte Biology · 1993 · 870 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.

Nitric oxide as a secretory product of mammalian cells · Scinovex