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CHEM21 selection guide of classical- and less classical-solvents

Green Chemistry · 2015 · Vol. 18(1) · pp. 288–296
Denis PratA.S. WellsJohn HaylerHelen F. SneddonCon Robert McElroySarah Abou‐ShehadaPeter J. Dunn

Abstract

A methodology, based on a combination of SH&E criteria, enables a simplified greenness evaluation of any solvent, in the context of fine or pharmaceutical chemistry.

Chemistry and Chemical EngineeringComputational Drug Discovery MethodsChemical Synthesis and AnalysisSelection (genetic algorithm)Context (archaeology)SolventBiochemical engineeringChemistryComputer scienceCombinatorial chemistryProcess engineeringComputational chemistryOrganic chemistry

Funding

  • Pfizer
  • Sanofi
  • European Federation of Pharmaceutical Industries and Associations
  • European Commission
  • Innovative Medicines Initiative
  • Seventh Framework Programme
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