articleTop 1% cited

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Journal of Pharmacology and Experimental Therapeutics · 1992 · Vol. 260(1) · pp. 275–285

Robert B. Raffa✉(Springhouse)Elmar Friderichs(Springhouse)Wolfgang Reimann(Springhouse)Richard P. Shank(Springhouse)E E Codd(Springhouse)J. L. Vaught(Springhouse)

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Veterinary Pharmacology and Anesthesia Pain Mechanisms and Treatments Receptor Mechanisms and SignalingTramadolED50Morphine(+)-NaloxoneOpioidPharmacologyOpioid receptorAnalgesicNociceptionChemistry

MeSH terms

AnimalsDose-Response Relationship, DrugKineticsMaleMice, Inbred StrainsNociceptorsPain MeasurementRats, Inbred StrainsReceptors, OpioidTramadolYohimbineRitanserinReceptors, Opioid, muReceptors, Opioid, deltaReceptors, Opioid, kappa

Citations

1,165

FWCI

26.41

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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