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Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities

Bioorganic & Medicinal Chemistry Letters · 2015 · Vol. 25(23) · pp. 5520–5523
Jing LiYun‐Peng SuiJiajia XinXin-Liang DuJiangtao LiHai-Ru HuoHai MaWei-Hao WangHaiyu ZhouHong-Dan ZhanZhuju WangQing LiFeng SuiXia Li
Synthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Biological ActivityDihydropyranChemistryStaphylococcus aureusApoptosisCell cultureAntibacterial agentAntibacterial activityStereochemistryMicrobiologyBiochemistry

MeSH terms

Anti-Bacterial AgentsAntineoplastic AgentsCoumarinsHumansMicrobial Sensitivity TestsModels, MolecularPyransStaphylococcus aureusCarboplatinApoptosisCrystallography, X-RayInhibitory Concentration 50Cell Line, TumorCell Proliferation

Funding

  • National Natural Science Foundation of China
  • Natural Science Foundation of Beijing Municipality
Citations
325
FWCI
5.05
field-weighted impact
References
21
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References
Global cancer statistics
CA A Cancer Journal for Clinicians · 2011 · 55,006 citations
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Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities · Scinovex