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Automated generation of heuristics for biological sequence comparison

BMC Bioinformatics · 2005 · Vol. 6(1) · pp. 31–31
Guy SlaterEwan Birney

Abstract

This system allows rapid implementation of heuristics approximating to many complex alignment models, and has been incorporated into the freely available sequence alignment program, exonerate.

Genomics and Phylogenetic StudiesGenome Rearrangement AlgorithmsProtein Structure and DynamicsHeuristicsComputational biologyDNA microarrayComputer scienceSequence (biology)BiologyGeneticsGene

MeSH terms

AlgorithmsArtificial IntelligenceAutomationComputer SimulationDNAHumansMathematical ComputingModels, BiologicalModels, TheoreticalRNA, MessengerSoftwareDatabases, FactualInformation Storage and RetrievalSequence AlignmentGenome
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References
Basic local alignment search tool
Journal of Molecular Biology · 1990 · 93,570 citations
An improved algorithm for matching biological sequences
Journal of Molecular Biology · 1982 · 1,751 citations
Identification of common molecular subsequences
Journal of Molecular Biology · 1981 · 10,021 citations
Efficient string matching
Communications of the ACM · 1975 · 2,924 citations
GeneWise and Genomewise
Genome Research · 2004 · 3,009 citations
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