article Open AccessTop 10% cited
Assessment of Clinical Complete Response After Chemoradiation for Rectal Cancer with Digital Rectal Examination, Endoscopy, and MRI: Selection for Organ-Saving Treatment
Annals of Surgical Oncology · 2015 · Vol. 22(12) · pp. 3873–3880
Monique Maas✉(Maastricht University Medical Centre)Doenja M. J. Lambregts(Maastricht University Medical Centre)Patty J. Nelemans(Maastricht University Medical Centre)Luc A. Heijnen(Maastricht University Medical Centre)Milou H. Martens(Maastricht University Medical Centre)Jeroen W. A. Leijtens(Laurentius Ziekenhuis)Meindert N. Sosef(Atrium Medisch Centrum Parkstad)Karel W. E. HulsewéChristiaan Hoff(Medisch Centrum Leeuwarden)Stéphanie O. Breukink(Maastricht University Medical Centre)Laurents P. S. Stassen(Maastricht University Medical Centre)Geerard L. Beets(Maastricht University Medical Centre)Geerard L. Beets(Maastricht University Medical Centre)
Abstract
Clinical assessment after CRT is the single most accurate modality for identification of CR after CRT. Addition of MRI with DWI further improves the diagnostic performance, and the combination can be recommended as the optimal strategy for a safe and accurate selection of CR after CRT.
Colorectal Cancer Surgical TreatmentsColorectal Cancer Screening and DetectionColorectal and Anal CarcinomasMedicineRectal examinationRadiologyReceiver operating characteristicColorectal cancerEndoscopyProspective cohort studyBiopsySurgical oncologyConfidence interval
MeSH terms
AdenocarcinomaAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProctoscopyProspective StudiesRectal NeoplasmsRemission InductionROC CurveTreatment OutcomeDisease-Free Survival
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374
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9.91
field-weighted impact
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31
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99%
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References
Diffusion-Weighted MRI for Selection of Complete Responders After Chemoradiation for Locally Advanced Rectal Cancer: A Multicenter Study
Annals of Surgical Oncology · 2011 · 384 citations
Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting
European Radiology · 2017 · 1,023 citations
Local Recurrence After Complete Clinical Response and Watch and Wait in Rectal Cancer After Neoadjuvant Chemoradiation: Impact of Salvage Therapy on Local Disease Control
International Journal of Radiation Oncology*Biology*Physics · 2014 · 619 citations
Complete Clinical Response After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer: Characterization of Clinical and Endoscopic Findings for Standardization
Diseases of the Colon & Rectum · 2010 · 448 citations
A method of comparing the areas under receiver operating characteristic curves derived from the same cases.
Radiology · 1983 · 7,066 citations
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
The Lancet Oncology · 2010 · 1,927 citations
Operative Versus Nonoperative Treatment for Stage 0 Distal Rectal Cancer Following Chemoradiation Therapy
Annals of Surgery · 2004 · 1,861 citations
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