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A comparison of the cardiovascular effects of levobupivacaine and rac‐bupivacaine following intravenous administration to healthy volunteers
British Journal of Clinical Pharmacology · 1998 · Vol. 46(3) · pp. 245–249
Abstract
In conclusion, this study has shown that following i.v. administration levobupivacaine produces significantly less effects on cardiovascular function than does rac-bupivacaine. In particular the negative inotropic effect for levobupivacaine was less than that for rac-bupivacaine as indicated by changes in stroke index, acceleration index and ejection fraction.
Anesthesia and Pain ManagementAnesthesia and Sedative AgentsCardiac, Anesthesia and Surgical OutcomesLevobupivacaineMedicineBupivacaineAnesthesiaHeart rateCrossover studyCardiac indexBlood pressureHemodynamicsEjection fraction
MeSH terms
AdultAnesthetics, LocalBlood PressureBupivacaineCardiovascular SystemHumansInfusions, IntravenousMaleStereoisomerismCross-Over Studies
Citations
423
FWCI
11.31
field-weighted impact
References
16
Percentile
99%
vs. same field & year
Citations per year
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References
Acute Toxicity of Ropivacaine Compared with That of Bupivacaine
Anesthesia & Analgesia · 1989 · 766 citations
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