articleTop 1% cited

Elevated levels of tumour necrosis factor (TNF)-α, interleukin (IL)-1β and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-α and IL-1β

British Journal of Dermatology · 2011 · Vol. 164(6) · pp. 1292–1298

Hessel H. van der Zee✉(Erasmus MC)L de Ruiter(Erasmus MC)D.G. van den Broecke(Diakonessenhuis hospital)Willem A. Dik(Erasmus MC)Jon D. Laman(Erasmus MC)Errol P. Prens(Erasmus MC)

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Abstract

This study shows for the first time that IL-1β, TNF-α and IL-10 levels are elevated in HS skin. These data provide a rationale for therapies with biologics targeting cytokines such as TNF-α and IL-1.

Hidradenitis Suppurativa and Treatments Acne and Rosacea Treatments and Effects Dermatological and COVID-19 studiesErasmus+Hidradenitis suppurativaMedicineTumor necrosis factor alphaAdalimumabClassicsDermatologyLibrary scienceInternal medicineArt history

MeSH terms

AdultCells, CulturedFemaleHumansMaleMiddle AgedPsoriasisSkinTumor Necrosis Factor-alphaCase-Control StudiesInterleukin-10Hidradenitis SuppurativaInterleukin-1beta

Citations

466

FWCI

17.67

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

References

Hidradenitis suppurativa: A comprehensive review