article Open AccessTop 1% cited
FAK integrates growth-factor and integrin signals to promote cell migration
Nature Cell Biology · 2000 · Vol. 2(5) · pp. 249–256
David J. Sieg✉(Scripps Research Institute)Christof R. Hauck(Scripps Research Institute)Duško Ilić(University of California, San Francisco)Candice K. Klingbeil(Scripps Research Institute)Erik SchaeferCaroline H. Damsky(University of California, San Francisco)David D. Schlaepfer(Scripps Research Institute)
Cell Adhesion Molecules ResearchCellular Mechanics and InteractionsPlatelet Disorders and TreatmentsFocal adhesionCell biologyProto-oncogene tyrosine-protein kinase SrcPlatelet-derived growth factor receptorIntegrinEpidermal growth factorSignal transductionGrowth factor receptorCancer researchCell migration
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References
Integrin signaling and cell growth control
Current Opinion in Cell Biology · 1998 · 657 citations
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation.
Molecular Biology of the Cell · 1996 · 508 citations
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin
Development · 1993 · 1,303 citations
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