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Body Mass Index, Serum Sex Hormones, and Breast Cancer Risk in Postmenopausal Women

JNCI Journal of the National Cancer Institute · 2003 · Vol. 95(16) · pp. 1218–1226
Endogenous Hormones Breast Cancer Collaborative Group

Abstract

The results are compatible with the hypothesis that the increase in breast cancer risk with increasing BMI among postmenopausal women is largely the result of the associated increase in estrogens, particularly bioavailable estradiol.

Cancer Risks and FactorsMetabolism, Diabetes, and CancerNutritional Studies and DietEstroneDehydroepiandrosterone sulfateBreast cancerSex hormone-binding globulinBody mass indexMedicineInternal medicineEstrone sulfateEndocrinologyEstrogen

MeSH terms

AgedBreast NeoplasmsEstradiolFemaleHumansMiddle AgedProspective StudiesRisk FactorsGonadal Steroid HormonesBody Mass IndexLogistic ModelsCase-Control StudiesPostmenopauseRisk Assessment

Funding

  • Brigham and Women's Hospital
  • University of Southern California
  • University of Missouri
  • University of Connecticut
  • Johns Hopkins University
  • University of Pittsburgh
  • Kagoshima University
  • York University
  • University of Oxford
  • School of Medicine, New York University
  • University of California, San Francisco
  • University at Buffalo
  • National Cancer Institute
  • Division of Cancer Epidemiology and Genetics, National Cancer Institute
Citations
1,084
FWCI
21.39
field-weighted impact
References
28
Percentile
100%
vs. same field & year
Citations per year
References
Endogenous Sex Hormones and Breast Cancer in Postmenopausal Women: Reanalysis of Nine Prospective Studies
JNCI Journal of the National Cancer Institute · 2002 · 1,789 citations
Overweight as an avoidable cause of cancer in Europe
International Journal of Cancer · 2001 · 750 citations
Pooled Analysis of Prospective Cohort Studies on Height, Weight, and Breast Cancer Risk
American Journal of Epidemiology · 2000 · 1,026 citations
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