article Open AccessTop 1% cited
The capsaicin receptor: a heat-activated ion channel in the pain pathway
Nature · 1997 · Vol. 389(6653) · pp. 816–824
Michael J. Caterina✉Mark Schumacher(University of California, San Francisco)Makoto Tominaga(Cellular Research (United States))Tobias A. Rosen(Cellular Research (United States))Jon D. Levine(University of California, San Francisco)David Julius(Cellular Research (United States))
Ion Channels and ReceptorsPain Mechanisms and TreatmentsIon channel regulation and functionCapsaicinChemistryIon channelReceptorTransient receptor potential channelTRPV1PharmacologyBiophysicsMedicineBiology
MeSH terms
Afferent PathwaysAmino Acid SequenceAnimalsCalciumCapsaicinCapsicumCell LineCloning, MolecularElectrophysiologyHot TemperatureHumansIon ChannelsMolecular Sequence DataNeurons, AfferentNeurotoxins
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References
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium
Journal of Neuroscience · 1993 · 1,463 citations
Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin
British Journal of Pharmacology · 1992 · 582 citations
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