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A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

The EMBO Journal · 1996 · Vol. 15(2) · pp. 290–298

Vladimir Joukov✉(Institute of Virology of the Slovak Academy of Sciences)Katri Pajusola(Institute of Virology of the Slovak Academy of Sciences)Arja Kaipainen(Institute of Virology of the Slovak Academy of Sciences)Dmitri Chilov(Institute of Virology of the Slovak Academy of Sciences)Isto Lahtinen(Institute of Virology of the Slovak Academy of Sciences)Eola Kukk(Institute of Virology of the Slovak Academy of Sciences)Olli Saksela(Institute of Virology of the Slovak Academy of Sciences)Nisse Kalkkinen(Institute of Virology of the Slovak Academy of Sciences)Kari Alitalo(Institute of Virology of the Slovak Academy of Sciences)

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Angiogenesis and VEGF in Cancer Vascular Tumors and Angiosarcomas Lymphoma Diagnosis and TreatmentReceptor tyrosine kinaseLibrary scienceBiologyVirologyKinaseGeneticsComputer science

MeSH terms

Amino Acid SequenceLigandsMolecular Sequence DataProto-Oncogene ProteinsEndothelial Growth FactorsReceptors, Growth FactorReceptor Protein-Tyrosine KinasesReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor Receptor-1

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Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis