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Cognitive Behavioral Therapy for Insomnia Enhances Depression Outcome in Patients with Comorbid Major Depressive Disorder and Insomnia

SLEEP · 2008 · Vol. 31(4) · pp. 489–495
Rachel ManberJack D. EdingerJenna L. GressMelanie G. San Pedro-SalcedoTracy F. KuoTasha Kalista

Abstract

This pilot study provides evidence that augmenting an antidepressant medication with a brief, symptom focused, cognitive-behavioral therapy for insomnia is promising for individuals with MDD and comorbid insomnia in terms of alleviating both depression and insomnia.

Sleep and related disordersMental Health Research TopicsTryptophan and brain disordersInsomniaActigraphyMajor depressive disorderCognitive behavioral therapy for insomniaEscitalopramCognitive behavioral therapyDepression (economics)PsychiatryPsychologyAntidepressant

MeSH terms

AdultDepressive Disorder, MajorMajor Depressive DisorderFemaleHumansSleep Initiation and Maintenance DisordersMalePilot ProjectsRemission InductionCitalopramComorbidityCognitive Behavioral TherapyTreatment OutcomeSelective Serotonin Reuptake Inhibitors

Funding

  • Jazz Pharmaceuticals
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